The perform of Medicinal Chemistry, Fourth version provides a pragmatic and accomplished evaluate of the day-by-day concerns dealing with pharmaceutical researchers and chemists. as well as its thorough therapy of simple medicinal chemistry rules, this up-to-date variation has been revised to supply new and accelerated insurance of the newest applied sciences and methods in drug discovery.
With themes like excessive content material screening, scoring, docking, binding unfastened strength calculations, polypharmacology, QSAR, chemical collections and databases, and masses extra, this booklet is the go-to reference for all educational and pharmaceutical researchers who want a whole knowing of medicinal chemistry and its program to drug discovery and development.
- Includes up to date and elevated fabric on platforms biology, chemogenomics, computer-aided drug layout, and different vital contemporary advances within the field
- Incorporates large colour figures, case reviews, and sensible examples to assist clients achieve one other figuring out of key options
- Provides top quality content material in a complete demeanour, together with contributions from overseas bankruptcy authors to illustrate the worldwide nature of medicinal chemistry and drug improvement research
- An photograph financial institution is on the market for teachers at www.textbooks.elsevier.com
Read or Download The Practice of Medicinal Chemistry, Fourth Edition PDF
Best Toxicology books
This guide, which in its early lustrous years served physicians, pharmacists, and pharmacy scholars, is not like the other drug reference booklet in that it permits readers to check and distinction numerous medications inside of drug different types, thereby allowing them to make judgements on which drug to manage. All different drug reference books only repeat the drug brands' literature, without research of that info.
The whole consultant to facing mould on your home--the asbestos of the recent millennium poisonous mould infestations in the house were dropped at the vanguard of public information. Erin Brockovich's fight to struggle this future health drawback and Ed McMahon's event of this challenge in his own residence have additional publicized the truth that mildew has been associated with a bunch of great illnesses.
The speedily increasing box of nutrition protection comprises many new advancements within the knowing of the whole diversity of poisonous compounds present in meals -- no matter if clearly taking place or having been brought by way of or meals processing equipment. This 2e of creation to foodstuff Toxicology explores those advancements whereas carrying on with to supply a middle realizing of the elemental rules of nutrition toxicology.
This new quantity of Advances in Pharmacology explores the present ideas in drug metabolism and toxicology. Chapters hide the Keap1-Nrf2 mobilephone safeguard pathway, animal types of drug-induced idiosyncratic toxicity and using human embryonic and prompted pluripotent stem cells for modeling metabolism and toxicity.
Extra resources for The Practice of Medicinal Chemistry, Fourth Edition