Even though there are various books on drug metabolism, Radiotracers in Drug Development is exclusive in explaining how radiotracers are used to explain a drug’s absorption, distribution, metabolism, and excretion (ADME). overlaying conventional and up to date applied sciences and purposes, the booklet takes a powerful business strategy, discussing the fundamentals of scintillation counting and untangling many of the facts processing tools frequently particular to person brands.
The chapters contain descriptions of the most recent micro-plate counters and the transforming into functions of accelerator mass spectrometry, positron emission tomography, gamma-scintigraphy, and radioluminography. as well as describing how the analytical applied sciences paintings, the members clarify how the knowledge are interpreted and utilized in the drug registration strategy.
A exact reference and coaching reduction crucial for each drug metabolism division or drug metabolism learn workforce, the e-book presents perception into the use and perform of ADME in a manner that's either instructive and sensible. relocating simply around the barriers of biology, chemistry, and physics, this is often the single accomplished, interdisciplinary source masking the how-tos of making use of radiotracers in drug improvement. It presents designated details on how the technology is suitable to the registration process.
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