The aim of the publication is to introduce platelets, and their practical function in thrombotic and heart problems, justifying the relevance of platelet proteomics study. concentration then shifts to the hot advancements on mass spectrometry (MS)-based proteomics. This bankruptcy exhibits strength purposes for platelet proteomics no longer but carried out. It contains examples of post-translational differences (PTMs) research in platelets.
The moment a part of the ebook specializes in the most examine performed thus far on platelet proteomics. This contains basic proteome mapping by way of non-gel dependent separation equipment (MudPit), research of the overall platelet proteome and signaling cascades by way of gel-based separation tools (2-DE), sub-proteome analyses (secretome/releasate, membrane proteins, organelles). ultimately, the final part hyperlinks the platelet transcriptome and alertness to disease. This part is extremely appropriate and contains chapters on proteomics, transcriptomics, practical genomics, platforms biology, and their purposes to platelet-related diseases.
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