By David A.D. Parry, John M. Squire
This e-book offers the readers with an up to date evaluation of the layout, constitution and serve as of a consultant number of fibrous proteins in either healthiness and illness. the significance of the α-helical coiled coil, a conformational motif in accordance with the heptad repeat within the amino acid series of all α-fibrous proteins (and elements of a few globular proteins) is underlined by way of 3 Chapters dedicated to its layout, constitution, functionality and topology. particular proteins coated within the textual content and which rely on the coiled coil for his or her constitution and serve as, comprise the intermediate filament proteins, tropomyosin, myosin, paramyosin, fibrin and individuals of the spectrin superfamily. additionally defined are fibrous proteins in response to the β-pleated sheet and collagen conformations. Recombinant structural proteins, in particular of silk and collagen, are mentioned within the context of constructing new biomaterials with diverse purposes.
Established researchers and postgraduate scholars within the fields of protein chemistry, biochemistry and structural biophysics will locate Fibrous Proteins: constructions and Mechanisms to be a useful choice of topical reports that describe the fundamental advances made within the box of fibrous proteins over the last decade. This ebook, written by means of famous experts within the box, offers a transparent account of the present prestige of fibrous protein learn and, additionally, establishes the root for finding out the main applicable instructions for destiny job, together with the functions of protein engineering and the industrial exploitation of latest biomaterials.
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