Download E-books Cyclic Nucleotides: Part I: Biochemistry PDF

By T. W. Rall (auth.), Professor Dr. J. A. Nathanson, Dr. J. W. Kebabian (eds.)

The goal of the current quantity, the 1st of 2 at the pharmacology, biochemistry, and body structure of cyclic nucleotides, is to supply a complete and up to date anthology at the nature and function of those very important chemical regulators. all the chapters is the paintings of across the world identified researchers who current a lucid and targeted evaluate in their topic and never purely a unmarried laboratory's point of view. The chapters emphasize serious tests of the sphere instead of mere listings of experimental findings. via so doing, the members current the position of cyclic nucleotides in courting to different intracellular regulators. each one bankruptcy starts off with an in depth precis to permit the reader to acquire a speedy assessment of next fabric. moreover, there are vast bibliographies and a close topic index. anyplace pertinent, the chapters include sections on drug mechanisms, physiological relevance, and illness procedures. the quantity is split into sections, each one starting with an summary written via Professors T. W. RALL and P. GREENGARD, respectively. the 1st part specializes in the precise pharmacology and chemistry of cyclic nucleotides, together with their formation, degradation, dimension, and interplay with a variety of modulatory brokers, reminiscent of receptors and calcium. the second one part is anxious with the biochemistry of protein phosphorylation, a technique which seems to be some of the most very important mechanisms for the intracellular expression of cyclic nucleotide motion in eukaryotic cells.

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