Biochemistry

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This booklet represents a collaborative activity by means of a bunch of investigators to collect in one quantity a serious dialogue of the main aspects of our wisdom, starting from chemical to medical points, of steroid conjugation. although, the $64000 box of bile acid and bile alcohol conjugation has been mentioned merely superficially because it was once made up our minds arbitrarily to be outdoors the projected scope of the publication. The reader is observed the better half quantity of this e-book, particularly actual homes of Steroid Conjugates (by Bernstein, Dusza, and Joseph, Springer-Verlag long island 1968), for complemental details on person conjugates. The Editors desire to thank pass over Elise Kramer for typing suggestions. additionally we want to convey our deep appreciation and gratitude to Mrs. Dorothy Budd, our copy-editor, and Mr. J. Joseph for his or her editorial tips in making this publication attainable. Pearl River, N. Y. SEYMOUR BERNSTEIN January, 1970 SAMUEL SOLOMON V1l CONTENTS Preface. . . . VlI Nomenclature a, dialogue of Nomenclature approach x b, Trivial and Systematic Names. x record of individuals . . . . . . . . Xl Chemistry: Synthesis and Characterization S. BERNSTEIN, J. P. DUSZA, and J. P. JOSEPH Enzymological points of Steroid Conjugation A. B. Roy . . . . . . . . . . seventy four The Hydrolysis of Steroid Conjugates H. L. BRADLOW . • . • . 131 Isolation of Steroid Conjugates P. ok. SUTERI. . . . . . . 182 The Biochemistry of the three p-Hydroxy-L1s-Steroid Sulfates ok. D. ROBERTS and S. LIEBERMAN 219 Formation, Metabolism, and shipping of Estrogen Conjugates E. DICZFALUSY and M. LEVITZ. • . . • . . . . • . . .

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